Article

Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in <i>EGFR</i> mutant lung cancer

2020-10-27

Abstract excerpt

Molecularly targeted cancer therapy has improved outcomes for cancer patients with targetable oncoproteins, such as mutant epidermal growth factor receptor ( EGFR ) in lung cancer. Yet, long-term patient survival remains limited because treatment responses are typically incomplete. One potential explanation for the lack of complete and durable responses is that oncogene-driven cancers with activating mutations i...

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Literature Corpus work: 27154d79-227d-55d4-8ef1-3f2bcd9eb220
DOI: 10.1101/2020.10.26.356352

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