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An mRNA–Lipid Nanoparticle Platform Encoding the Conserved Outer Membrane Protein BamA Elicits Broadly Cross-Reactive Systemic and Mucosal Antibodies Against Antimicrobial-Resistant <i>Neisseria gonorrhoeae</i>

2026-07-16

Abstract excerpt

Neisseria gonorrhoeae ( Ng ) is the causative agent of gonorrhea, and the global spread of antimicrobial-resistant strains makes vaccine development a public health priority. Although messenger RNA (mRNA) vaccines have transformed protection against viral diseases, the platform remains in its infancy against pathogenic bacteria. Here, we evaluated the immunogenicity and protective efficacy of an mRNA–lipid nanopa...

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Literature Corpus work
26feee49-739d-544f-a54a-1cb698f6c6ef
DOI
10.64898/2026.07.14.738439
Open publication

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An mRNA–Lipid Nanoparticle Platform Encoding the Conserved Outer Membrane Protein BamA Elicits Broadly Cross-Reactive Systemic and Mucosal Antibodies Against Antimicrobial-Resistant <i>Neisseria gonorrhoeae</i>DOI 10.64898/2026.07.14.738439
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