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Meningococcal vaccine Bexsero elicits a robust cellular immune response that targets but is not consistently protective against <i>Neisseria gonorrhoeae</i> during murine vaginal infection

2024-09-13

Abstract excerpt

Retrospective epidemiological studies suggest that the licensed serogroup B meningococcal vaccine 4CMenB (Bexsero) provides some protection against the closely related pathogen Neisseria gonorrhoeae in humans. This result has been replicated in murine models of gonococcal colonization, with a gonococci-reactive humoral response and more rapid clearance of vaginal infection. However, immunization with Bexsero cons...

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Literature Corpus work
fd3a4295-933a-5869-9e29-458ce71f114a
DOI
10.1101/2024.09.08.611931
Open publication

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