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Neisseria gonorrhoeae: Drug Resistance, Mouse Models, and Vaccine Development

8 Sept 2017

Abstract excerpt

Gonorrhea, an obligate human infection, is on the rise worldwide and gonococcal strains resistant to many antibiotics are emerging. Appropriate antimicrobial treatment and prevention, including effective vaccines, are urgently needed. To guide investigation, an experimental model of genital tract infection has been developed in female mice to study mechanisms by which Neisseria gonorrhoeae evades host-derived...

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PMID: 28886683
DOI: 10.1146/annurev-micro-090816-093530

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