Back to search

Article

Integrated T-Cell Receptor Repertoire and Tumor Immunogenicity Profiling Reveals Distinct Immunogenomic States in Endometrial Cancer

2026-06-10

Abstract excerpt

<h4>Background</h4> Endometrial cancer exhibits marked molecular and immune heterogeneity that is only partially explained by established genomic biomarkers. We investigated whether T-cell receptor (TCR) repertoire architecture captures complementary dimensions of antitumor immunity beyond conventional molecular classification. <h4>Methods</h4> Paired tumor and peripheral blood samples from eight patients with m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
26f6af73-4c99-52ab-ae9f-911d8df35cf2
DOI
10.64898/2026.06.08.26355191
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Integrated T-Cell Receptor Repertoire and Tumor Immunogenicity Profiling Reveals Distinct Immunogenomic States in Endometrial CancerDOI 10.64898/2026.06.08.26355191
Tumor immune microenvironment in endometrial cancer of different molecular subtypes: evidence from a retrospective observational study.Semantic proximity
The Immune Landscape of CancerSemantic proximity
Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancerSemantic proximity
Immune checkpoint expression, microsatellite instability, and mutational burden: Identifying immune biomarker phenotypes in uterine cancer.Semantic proximity
The interface of malignant and immunologic clonal dynamics in high-grade serous ovarian cancerSemantic proximity
Proteogenomic and single-cell dissection of immune heterogeneity in NSMP endometrial cancer reveals dual IDO1 programsSemantic proximity
Distinct Immunological Landscapes Characterize Inherited and Sporadic Mismatch Repair Deficient Endometrial CancerSemantic proximity
Unveiling immunogenic characteristics and neoantigens in endometrial cancer with POLE hotspot mutations for improved immunotherapySemantic proximity
Understanding the Impact of Spatial Immunophenotypes on the Survival of Endometrial Cancer Patients through the ProMisE ClassificationSemantic proximity
Immune and malignant cell phenotypes of ovarian cancer are determined by distinct mutational processesSemantic proximity
Desert Immune Phenotype in Endometrial Carcinoma: A Distinct Subgroup With Poor Prognosis and Targetable Mutations.Semantic proximity
Integrated Immunophenotypic and ProMisE Molecular Profiling as Predictors of Immune Checkpoint Inhibitor Response in Endometrial CancerSemantic proximity
Select a neighboring publication to make it the new centre.