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Proteogenomic and single-cell dissection of immune heterogeneity in NSMP endometrial cancer reveals dual IDO1 programs

2026-05-13

Abstract excerpt

<title>Abstract</title> <p>The no-specific-molecular-profile (NSMP) subtype is the largest and most clinically heterogeneous group of endometrial cancers, but its immune microenvironment remains poorly characterised. Integrating transcriptomic (TCGA-UCEC; n = 145), genomic (MSK-IMPACT; n = 108), proteogenomic (CPTAC-UCEC; n = 43) and paired-sample single-cell (GSE251923; 17,539 cells) data, we show that NSMP harb...

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Literature Corpus work
a7624462-b894-51dd-b8b5-39e7b08aae5e
DOI
10.21203/rs.3.rs-9688861/v1
Open publication

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Proteogenomic and single-cell dissection of immune heterogeneity in NSMP endometrial cancer reveals dual IDO1 programsDOI 10.21203/rs.3.rs-9688861/v1
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