Article
Immune checkpoint expression, microsatellite instability, and mutational burden: Identifying immune biomarker phenotypes in uterine cancer.
Gynecologic oncology - 1 Feb 2020
Jones Nathaniel L, Xiu Joanne, Rocconi Rodney P, Herzog Thomas J, Winer Ira S
Abstract excerpt
OBJECTIVES: Increasing grade of endometrioid endometrial cancer (EEC) is associated with aggressive behavior and poor prognosis. The traditional classification system is limited in its ability to guide treatment planning and prognostication. We identify distinct immune biomarker phenotypes using known markers of immunogenicity to identify patients who may benefit from immune therapy (IT). METHODS: 621 tumors were...
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