Article
Coordination of microtubule acetylation and the actin cytoskeleton by formins.
Cellular and molecular life sciences : CMLS - 1 Sept 2018
Fernández-Barrera Jaime, Alonso Miguel A
Abstract excerpt
The acetylation of the lysine 40 residue of α-tubulin was described more than 30 years ago and has been the subject of intense research ever since. Although the exact function of this covalent modification of tubulin in the cell remains unknown, it has been established that tubulin acetylation confers resilience to mechanical stress on the microtubules. Formins have a dual role in the fate of the actin and...
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