Article
Identification of the human N(alpha)-acetyltransferase complex B (hNatB): a complex important for cell-cycle progression.
The Biochemical journal - 15 Oct 2008
Starheim Kristian K, Arnesen Thomas, Gromyko Darina, Ryningen Anita, Varhaug Jan Erik, Lillehaug Johan R
Abstract excerpt
Protein N(alpha)-terminal acetylation is a conserved and widespread protein modification in eukaryotes. Several studies have linked it to normal cell function and cancer development, but nevertheless, little is known about its biological function. In yeast, protein N(alpha)-terminal acetylation is performed by the N-acetyltransferase complexes NatA, NatB and NatC. In humans, only the NatA complex has been...
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