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Synergistic Effects of Micropatterned Substrates and Transforming Growth factor-β1 on Differentiation of Human Mesenchymal Stem Cells into Vascular Smooth Muscle Cells through Modulation of Krϋppel-like Factor 4

2024-09-30

Abstract excerpt

The functionality and structural integrity of the cardiovascular system profoundly depend on vascular smooth muscle cells (VSMCs). Human mesenchymal stem cells (hMSCs) have the potential to differentiate into VSMCs, which is promising for regenerative medicine and the production of vascular grafts. This study investigates the combined effect of micropatterned substrates and TGF-β1 on hMSC differentiation into VSMC...

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Literature Corpus work: 26cd2635-20cd-538d-b566-81b907038dc0
DOI: 10.22541/au.172768836.63720040/v1

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