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Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial

2024-09-22

Abstract excerpt

In idiopathic pulmonary fibrosis (IPF) patients, alveolar epithelium architectures are persistently lost and lung gas transfer function would decline over time, which cannot be rescued by conventional anti-fibrotic therapy. P63+ airway basal progenitor cells are previously reported to have great potential to repair damaged lung epithelium. Here, we successfully cloned and expanded the autologous P63+ progenitor ce...

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Identifiers and source

Literature Corpus work
26a504e9-0c48-5871-bef7-bc8d52ce111f
DOI
10.1101/2024.09.18.24313787
Open publication

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Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trialDOI 10.1101/2024.09.18.24313787
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