Article
CD166pos Subpopulation From Differentiated Human ES and iPS Cells Support Repair of Acute Lung Injury
11 Sept 2012
Abstract excerpt
Previous efforts to derive lung progenitor cells from human embryonic stem (hES) cells using embryoid body formation or stromal feeder cocultures had been limited by low efficiencies. Here, we report a step-wise differentiation method to drive both hES and induced pluripotent stem (iPS) cells toward the lung lineage. Our data demonstrated a 30% efficiency in generating lung epithelial cells (LECs) that expresses...
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