Article

Imputation of fluid intelligence scores reduces ascertainment bias and increases power for analyses of common and rare variants

2025-06-20

Abstract excerpt

Studying the genetics of intelligence can help us understand the neurobiology of cognitive function and the aetiology of rare neurodevelopmental conditions. The largest previous genetic studies of intelligence have used ~270k individuals who completed the fluid intelligence (FI) tests in UK Biobank. Here, we integrate additional FI measures in this cohort and leverage 82 correlated variables to impute FI values fo...

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Literature Corpus work: 26800603-c726-5103-a7aa-9ba0afb02422
DOI: 10.1101/2025.06.18.25329418

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