Article

Estimation of Vaccine Efficacy for Variants that Emerge After the Placebo Group Is Vaccinated

2021-09-02

Abstract excerpt

<h4>Summary</h4> SARS-CoV-2 continues to evolve and the vaccine efficacy against variants is challenging to estimate. It is now common in phase III vaccine trials to provide vaccine to those randomized to placebo once efficacy has been demonstrated, precluding a direct assessment of placebo controlled vaccine efficacy after placebo vaccination. In this work we extend methods developed for estimating vaccine effica...

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Literature Corpus work: 267a1f5b-015a-597a-bbe8-4dccca3417b8
DOI: 10.1101/2021.08.31.21262908

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