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Bayesian joint modelling framework linking antibody kinetics and test-negative vaccine effectiveness to study hybrid immunity across epidemic waves

2026-04-27

Abstract excerpt

Vaccine effectiveness against symptomatic SARS-CoV-2 infection varies over time and across epidemic waves. This variation can reflect waning immunity, immune escape by emerging variants, exposure heterogeneity, and differences in previous infection history. Test-negative case-control designs are widely used to monitor vaccine effectiveness, while longitudinal serological studies describe antibody trajectories afte...

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Literature Corpus work
a9d582e6-d536-508a-a5a5-953840174078
DOI
10.64898/2026.04.25.26351732
Open publication

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Bayesian joint modelling framework linking antibody kinetics and test-negative vaccine effectiveness to study hybrid immunity across epidemic wavesDOI 10.64898/2026.04.25.26351732
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