Article

RGS20 reduces glioma stemness and temozolomide resistance by intrinsically inhibiting the WNT/β-catenin signaling pathway

2025-03-04

Abstract excerpt

<title>Abstract</title> G protein-coupled receptors (GPCRs) play a pivotal role in maintaining the stemness of both normal and cancer stem cells. However, the function of the regulator of G protein signaling (RGS) family, particularly in tumor stem cells, remains poorly understood. Through bioinformatics analysis of clinical data, we identified RGS20 as a potential regulator of glioma stemness and temozolomide...

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Literature Corpus work: 2645d7fb-a5f3-5a87-8d7e-a9e08fb43919
DOI: 10.21203/rs.3.rs-6110723/v1

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