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Article

The Lactobacillus Bile Salt Hydrolase Repertoire Reveals Niche-Specific Adaptation.

mSphere - 27 Jun 2018

O'Flaherty Sarah, Briner Crawley Alexandra, Theriot Casey M, Barrangou Rodolphe

Abstract excerpt

Various Lactobacillus species have been reported to deconjugate bile acids in the gastrointestinal tract (GIT) through the action of bile salt hydrolase (BSH) proteins. This function contributes to altering the gut microbiota composition and bile metabolism and detoxification and to lowering cholesterol levels. Here, we investigated the Lactobacillus BSH repertoire across 170 sequenced species. We used hidden...

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Identifiers

PMID: 29848760
DOI: 10.1128/mSphere.00140-18
PMCID: PMC5976879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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