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Article

Early differential protein expression in blood and bronchoalveolar fluid among ARDS phenotypes.

Scientific reports - 22 Apr 2026

Wildi Karin, Bihari Shailesh, Bersten Andrew, Dixon Dani-Louise, Paul Eldho, McGuinness Shay, Hodgson Carol, Nichol Alistair, Chataway Timothy, Colella Alex D, Gebhard Caroline E, Chegeni Nusha, Matigian Nicholas, LiBassi Gianluigi, Passmore Margaret, Bouquet Mahé, Ritchie Alex, Suen Jacky, Fraser John

Abstract excerpt

Protein pathways underlying ARDS phenotypes are not fully elucidated. The aim of this subanalysis of an international randomized controlled clinical trial, which assessed the potential benefit of a maximal lung recruitment strategy, was to identify protein signatures in serum and bronchoalveolar fluid associated with ARDS phenotypes and to improve understanding of the underlying biological pathways. Whole...

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Identifiers

PMID: 42020568
DOI: 10.1038/s41598-026-43956-0
PMCID: PMC13273051

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