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Functional Pangenome Analysis Shows Key Features of E Protein Are Preserved in SARS and SARS-CoV-2.

Frontiers in cellular and infection microbiology - 1 Jan 2020

Alam Intikhab, Kamau Allan A, Kulmanov Maxat, Jaremko Łukasz, Arold Stefan T, Pain Arnab, Gojobori Takashi, Duarte Carlos M

Abstract excerpt

The spread of the novel coronavirus (SARS-CoV-2) has triggered a global emergency, that demands urgent solutions for detection and therapy to prevent escalating health, social, and economic impacts. The spike protein (S) of this virus enables binding to the human receptor ACE2, and hence presents a prime target for vaccines preventing viral entry into host cells. The S proteins from SARS and SARS-CoV-2 are...

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Identifiers

PMID: 32850499
DOI: 10.3389/fcimb.2020.00405
PMCID: PMC7396417

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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