Article

DNA methylation outlier burden, health and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936

2019-11-02

Abstract excerpt

DNA methylation outlier burden has been suggested as a potential marker of biological age. An outlier is typically defined as DNA methylation levels at any one CpG site that are three times beyond the inter-quartile range from the 25 th or 75 th percentiles compared to the rest of the population. DNA methylation outlier burden (the number of such outlier sites per individual) increases exponentially with age. Howe...

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Literature Corpus work: 2614e71c-8b34-572e-8928-b7c6b94eeace
DOI: 10.1101/19010728

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