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What’s counted counts: the implications of underrepresentation for the application of epigenetic clocks in diverse populations

3 Oct 2025

Abstract excerpt

DNA methylation (DNAm) has been touted as a potential unified marker of the contributions of both inherited and environmental factors on an individual's health. Changes in DNAm have been associated with several chronic diseases and mortality, and DNAm risk scores, or epigenetic clocks, have been proposed as metrics to quantify the process of 'biological ageing'. Unfortunately, research involving epigenetic clocks...

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PMID: 41044683
DOI: 10.1186/s13148-025-01954-5

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