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Article

Controversies around epithelial-mesenchymal plasticity in cancer metastasis.

Nature reviews. Cancer - 1 Dec 2019

Williams Elizabeth D, Gao Dingcheng, Redfern Andrew, Thompson Erik W

Abstract excerpt

Experimental evidence accumulated over decades has implicated epithelial-mesenchymal plasticity (EMP), which collectively encompasses epithelial-mesenchymal transition and the reverse process of mesenchymal-epithelial transition, in tumour metastasis, cancer stem cell generation and maintenance, and therapeutic resistance. However, the dynamic nature of EMP processes, the apparent need to reverse mesenchymal...

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Identifiers

PMID: 31666716
DOI: 10.1038/s41568-019-0213-x
PMCID: PMC7055151

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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