Oligometastases: Characterizing the Role of Epigenetic Regulation of Epithelial–Mesenchymal Transition

Abstract excerpt

The "oligometastasis" hypothesis proposes that metastases exist as a spectrum and are not always disseminated. According to this theory, a subset of patients with metastatic disease could benefit from aggressive local therapies. However, the identification of patients most likely to exhibit an oligometastatic phenotype remains challenging. Recent literature focusing on basic and translational studies has...

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