EMT and MET : necessary or permissive for metastasis?

doi:10.1002/1878-0261.12083

Article

EMT and MET : necessary or permissive for metastasis?

26 May 2017

Abstract excerpt

Epithelial-to-mesenchymal transition (EMT) and its reverse mesenchymal-to-epithelial transition (MET) have been suggested to play crucial roles in metastatic dissemination of carcinomas. These phenotypic transitions between states are not binary. Instead, carcinoma cells often exhibit a spectrum of epithelial/mesenchymal phenotype(s). While epithelial/mesenchymal plasticity has been observed preclinically and...

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