Article

Mechanisms of surface antigenic variation in the human pathogenic fungus <i>Pneumocystis jirovecii</i>

2017-07-03

Abstract excerpt

Microbial pathogens commonly escape the human immune system by varying surface proteins. We investigated the mechanisms used for that purpose by Pneumocystis jirovecii. This uncultivable fungus is an obligate pulmonary pathogen which causes pneumonia in immuno-compromised individuals, a major life-threatening infection. Long-read PacBio sequencing was used to assemble a core of subtelomeres of a single P. jirove...

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Literature Corpus work: 25ea880b-a7bb-51fb-8489-9ab4e0b923b3
DOI: 10.1101/158881

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