Article
Diversity and Complexity of the Large Surface Protein Family in the Compacted Genomes of Multiple Pneumocystis Species.
mBio - 3 Mar 2020
Ma Liang, Chen Zehua, Huang Da Wei, Cissé Ousmane H, Rothenburger Jamie L, Latinne Alice, Bishop Lisa, Blair Robert, Brenchley Jason M, Chabé Magali, Deng Xilong, Hirsch Vanessa, Keesler Rebekah, Kutty Geetha, Liu Yueqin, Margolis Daniel, Morand Serge, Pahar Bapi, Peng Li, Van Rompay Koen K A, Song Xiaohong, Song Jun, Sukura Antti, Thapar Sabrina, Wang Honghui, Weissenbacher-Lang Christiane, Xu Jie, Lee Chao-Hung, Jardine Claire, Lempicki Richard A, Cushion Melanie T, Cuomo Christina A, Kovacs Joseph A
Abstract excerpt
Pneumocystis, a major opportunistic pathogen in patients with a broad range of immunodeficiencies, contains abundant surface proteins encoded by a multicopy gene family, termed the major surface glycoprotein (Msg) gene superfamily. This superfamily has been identified in all Pneumocystis species characterized to date, highlighting its important role in Pneumocystis biology. In this report, through a comprehensive...
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