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Structural and functional alterations in the colonic microbiome of the rat in a model of stress induced irritable bowel syndrome

2 Jan 2017

Abstract excerpt

Stress is known to perturb the microbiome and exacerbate irritable bowel syndrome (IBS) associated symptoms. Characterizing structural and functional changes in the microbiome is necessary to understand how alterations affect the biomolecular environment of the gut in IBS. Repeated water avoidance (WA) stress was used to induce IBS-like symptoms in rats. The colon-mucosa associated microbiome was characterized in...

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PMID: 28059627
DOI: 10.1080/19490976.2016.1273999

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