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Prenatal Maternal Stress Exacerbates Experimental Colitis of Offspring in Adulthood

3 Nov 2021

Abstract excerpt

The prevalence of inflammatory bowel disease (IBD) is increasing worldwide and correlates with dysregulated immune response because of gut microbiota dysbiosis. Some adverse early life events influence the establishment of the gut microbiota and act as risk factors for IBD. Prenatal maternal stress (PNMS) induces gut dysbiosis and perturbs the neuroimmune network of offspring. In this study, we aimed to...

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PMID: 34804005
DOI: 10.3389/fimmu.2021.700995

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