Article
Evolutionary trace residues in noroviruses: importance in receptor binding, antigenicity, virion assembly, and strain diversity.
Journal of virology - 1 Jan 2005
Chakravarty Sugoto, Hutson Anne M, Estes Mary K, Prasad B V Venkataram
Abstract excerpt
Noroviruses cause major epidemic gastroenteritis in humans. A large number of strains of these single-stranded RNA viruses have been reported. Due to the absence of infectious clones of noroviruses and the high sequence variability in their capsids, it has not been possible to identify functionally important residues in these capsids. Consequently, norovirus strain diversity is not understood on the basis of...
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