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Mutations that positively affect <i>Bandavirus</i> glycoprotein function on VSV vectored vaccines

2026-04-16

Abstract excerpt

Severe fever with thrombocytopenia syndrome virus (SFTSV) and Heartland virus (HRTV) are emerging tick-borne bandaviruses. They have high case fatality rates (10%), and no FDA-approved vaccines exist for disease prevention. SFTSV and HRTV are therefore identified as priority pathogens. A recombinant vesicular stomatitis virus (rVSV) vaccine, which replaces the original VSV glycoprotein with the SFTSV glycoproteins...

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Identifiers and source

Literature Corpus work
24d63e5c-6b98-5c94-ae7c-4f55cbd88081
DOI
10.64898/2026.04.15.718665
Open publication

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Mutations that positively affect <i>Bandavirus</i> glycoprotein function on VSV vectored vaccinesDOI 10.64898/2026.04.15.718665
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