Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

N-glycosylation of viral glycoprotein is a novel determinant for the tropism and virulence of highly pathogenic tick-borne bunyaviruses

15 Jul 2024

Abstract excerpt

Severe fever with thrombocytopenia syndrome (SFTS) virus, a tick-borne bunyavirus, causes a severe/fatal disease termed SFTS; however, the viral virulence is not fully understood. The viral non-structural protein, NSs, is the sole known virulence factor. NSs disturbs host innate immune responses and an NSs-mutant SFTS virus causes no disease in an SFTS animal model. The present study reports a novel determinant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mosquito-borne diseases and control
Share to Vector-Borne Animal Diseases
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39008518
DOI: 10.1371/journal.ppat.1012348

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

N-glycosylation of viral glycoprotein is a novel determinant for the tropism and virulence of highly pathogenic tick-borne bunyavirusesPMID 39008518Read ↗

Effect of genomic variations in severe fever with thrombocytopenia syndrome virus on the disease lethalitySemantic proximity Read ↗

NSs: the multifaceted bunyavirus virulence factorSemantic proximity Read ↗

The Endless Wars: Severe Fever With Thrombocytopenia Syndrome Virus, Host Immune and Genetic FactorsSemantic proximity Read ↗

The Postfusion Structure of the Heartland Virus Gc Glycoprotein Supports Taxonomic Separation of the Bunyaviral Families Phenuiviridae and HantaviridaeSemantic proximity Read ↗

Mutations that positively affect <i>Bandavirus</i> glycoprotein function on VSV vectored vaccinesSemantic proximity Read ↗

The role of glycosylation patterns of viral glycoproteins and cell entry receptors in arenavirus infection.Semantic proximity Read ↗

Extracellular Vesicles Mediate Receptor-Independent Transmission of Novel Tick-Borne BunyavirusSemantic proximity Read ↗

Genotype-Dependent Virulence of Severe Fever with Thrombocytopenia Syndrome Virus in a Mouse Challenge Model.Semantic proximity Read ↗

Cryo-EM structure of severe fever with thrombocytopenia syndrome virusSemantic proximity Read ↗

Flavivirus Envelope Protein Glycosylation: Impacts on Viral Infection and PathogenesisSemantic proximity Read ↗

Human monoclonal antibodies that target the SFTSV glycoprotein Gn head from four neutralizing epitope groupsSemantic proximity Read ↗

Generation of Mutant Uukuniemi Viruses Lacking the Nonstructural Protein NSs by Reverse Genetics Indicates that NSs Is a Weak Interferon AntagonistSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.