Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single dose of a rVSV-based vaccine elicits complete protection against severe fever with thrombocytopenia syndrome virus

25 Jan 2019

Abstract excerpt

Severe fever with thrombocytopenia virus (SFTSV) is an emerging tick-borne phlebovirus that causes lethal human disease, for which there are no licensed antiviral vaccines or therapies. Herein, we developed a live attenuated recombinant vesicular stomatitis virus (rVSV)-based vaccine candidate expressing the SFTSV Gn/Gc glycoproteins (rVSV-SFTSV/AH12-GP). High titers of cross-protective, broadly neutralizing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mosquito-borne diseases and control
Share to Viral Infections and Outbreaks Research
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30701094
DOI: 10.1038/s41541-018-0096-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single dose of a rVSV-based vaccine elicits complete protection against severe fever with thrombocytopenia syndrome virusPMID 30701094Read ↗

Safety, Immunogenicity and Efficacy of a Recombinant Vesicular Stomatitis Virus Vectored Vaccine Against Severe Fever with Thrombocytopenia Syndrome Virus and Heartland BandavirusesSemantic proximity Read ↗

Heterologous vaccination utilizing viral vector and protein platforms confers complete protection against SFTSVSemantic proximity Read ↗

Heterologous prime-boost regimen elicits potent humoral and cell-mediated immune responses and provides complete protection against SFTSVSemantic proximity Read ↗

Serial Cell-Culture Passage of Severe Fever with Thrombocytopenia Syndrome Virus Attenuates Virulence and Confers Protective Immunity in Mice.Semantic proximity Read ↗

Cross-genotype protection of live-attenuated vaccine candidate for severe fever with thrombocytopenia syndrome virus in a ferret modelSemantic proximity Read ↗

Severe fever with thrombocytopenia syndrome virus: emerging novel phlebovirus and their control strategy.Semantic proximity Read ↗

Homologous and Heterologous Vaccination Regimens with mRNA and rVSV Platforms Induce Potent Immune Responses Against SFTSV GlycoproteinSemantic proximity Read ↗

A highly attenuated vaccinia virus strain LC16m8-based vaccine for severe fever with thrombocytopenia syndromeSemantic proximity Read ↗

Vaccination with single plasmid DNA encoding IL-12 and antigens of severe fever with thrombocytopenia syndrome virus elicits complete protection in IFNAR knockout miceSemantic proximity Read ↗

Effect of genomic variations in severe fever with thrombocytopenia syndrome virus on the disease lethalitySemantic proximity Read ↗

Mutations that positively affect <i>Bandavirus</i> glycoprotein function on VSV vectored vaccinesSemantic proximity Read ↗

The Endless Wars: Severe Fever With Thrombocytopenia Syndrome Virus, Host Immune and Genetic FactorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.