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MET-TKIs selectively inhibit growth of hepatobiliary carcinoma harboring high copy number MET amplification: 2 cases and literature review

2026-04-19

Abstract excerpt

<title>Abstract</title> <p>Objective To investigate the efficacy of highly selective MET-TKIs, targeting met exon14 skipping muation, in patients with hepatobiliary carcinoma harboring MET amplification. Methods Clinical data from two patients with advanced metastatic hepatobiliary carcinoma and MET gene amplification were collected. Literature review was conducted to analyze the clinical characteristics of the...

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Literature Corpus work
24b76b05-06fd-53b0-bf11-f9d68de24e76
DOI
10.21203/rs.3.rs-8898860/v1
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MET-TKIs selectively inhibit growth of hepatobiliary carcinoma harboring high copy number MET amplification: 2 cases and literature reviewDOI 10.21203/rs.3.rs-8898860/v1
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