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Gastric cancer patient with c-MET amplification treated with crizotinib after failed multi-line treatment: A case report and literature review

1 Jan 2019

Abstract excerpt

Gastric cancer is one of the most common gastrointestinal tumors. Most patients have been in advanced stage at diagnosis and lack effective treatment. Molecular targeted drugs have become new therapeutic strategies. MET is an important driving gene for the development of gastric cancer. MET gene amplification and protein over-expression are closely related to the invasion and metastasis, late stage and poor...

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PMID: 31499745
DOI: 10.3934/mbe.2019296

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