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Targeting MET Dysregulation in Cancer

12 Jun 2020

Abstract excerpt

gene amplification, mutation, rearrangement, and overexpression. Improvements in biomarker discovery and testing have more recently enabled the selection of patients with MET-dependent cancers for treatment with potent, specific, and novel MET-targeting therapies. We review the known oncologic processes that activate MET, discuss therapeutic strategies for MET-dependent malignancies, and highlight emerging...

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PMID: 32532746
DOI: 10.1158/2159-8290.cd-19-1446

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