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Article

Efficient generation of functional Schwann cells from adipose-derived stem cells in defined conditions.

Cell cycle (Georgetown, Tex.) - 3 May 2017

Xie Songtao, Lu Fan, Han Juntao, Tao Ke, Wang Hongtao, Simental Alfred, Hu Dahai, Yang Hao

Abstract excerpt

Schwann cells (SCs) are hitherto regarded as the most promising candidates for viable cell-based therapy to peripheral nervous system (PNS) injuries or degenerative diseases. However, the extreme drawbacks of transplanting autologous SCs for clinical applications still represent a significant bottleneck in neural regenerative medicine, mainly owing to the need of sacrificing a functional nerve to generate...

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Adipose Tissue
Cell Separation
Cell Shape
Myelin Sheath
Nerve Growth Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28296571
DOI: 10.1080/15384101.2017.1304328
PMCID: PMC5444349

Genes

BDNF
GDNF
GFAP
NGF

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