Article

The Impact of the PCSK-9 / VLDL-Receptor Axis on Inflammatory Cell Polarization

2021-07-30

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Studies have shown that lipoproteins, including LDL, VLDL, and ApoE2 have an impact on macrophage polarization, important to atherosclerosis progression. PCSK9 is a key mediator regulating the expression of lipoprotein receptors. The present study investigates the effect of the VLDL/VLDL-R axis on mononuclear cell polarization, as well as the role of PCSK9 and P...

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Literature Corpus work: 248f11d6-fdf0-581b-a292-4ff6332a7e7f
DOI: 10.21203/rs.3.rs-746511/v1

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