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T3 and Curcumin Regulates Collagen-IV and Collagen-VI Expression: Role in Suppression of Amyloid-β via TGFβ1-Sp1 Signaling in Hypothyroid Mice Brain

2026-06-23

Abstract excerpt

<title>Abstract</title> <p> Hypothyroidism has been associated with cognitive disorders and high risk of neurodegenerative disorders like Alzheimer's disease (AD), which is caused by amyloid-β (Aβ) accumulation in brain. The aim of the study is to examine the therapeutic ability of triiodothyronine (T <sub>3</sub> ) and curcumin in regulating two key extracellular matrix proteins (ECM), collagen IV and collage...

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Literature Corpus work
2488f8bb-a59c-5802-930b-3e7012c9f891
DOI
10.21203/rs.3.rs-9659339/v1
Open publication

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T3 and Curcumin Regulates Collagen-IV and Collagen-VI Expression: Role in Suppression of Amyloid-β via TGFβ1-Sp1 Signaling in Hypothyroid Mice BrainDOI 10.21203/rs.3.rs-9659339/v1
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