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Article

Innate immune activity in plaque of patients with untreated and L-thyroxine-treated subclinical hypothyroidism.

The Journal of clinical endocrinology and metabolism - 1 Apr 2011

Marfella Raffaele, Ferraraccio Franca, Rizzo Maria Rosaria, Portoghese Michele, Barbieri Michelangela, Basilio Crescenzo, Nersita Roberto, Siniscalchi Luisa Isabella, Sasso Ferdinando Carlo, Ambrosino Immacolata, Siniscalchi Mario, Maresca Lucio, Sardu Celestino, Amato Gianni, Paolisso Giuseppe, Carella Carlo

Abstract excerpt

CONTEXT: A strong association between subclinical hypothyroidism (SCH) and atherosclerotic diseases, independent of the traditional risk factors, was noted. OBJECTIVE: The objective of the study was to evaluate the association between SCH and the inflammatory potential of atherosclerotic plaques as well as the role of L-T(4) replacement therapy (LTR) on regulation of plaque inflammation. EXPERIMENTAL DESIGN AND...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21239513
DOI: 10.1210/jc.2010-1382

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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