Article

Adeno-associated virus mediated gene delivery: Implications for scalable <i>in vitro</i> and <i>in vivo</i> cardiac optogenetic models

2017-08-31

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Aims</h4> Adeno-associated viruses (AAVs) provide advantages in long-term, cardiac-specific gene expression. However, AAV serotype specificity data is lacking in cardiac models relevant to optogenetics. We aimed to identify the optimal AAV serotype (1, 6, or 9) in pursuit of scalable rodent and human models for cardiac optogenetics and elucidate the mechanism of virus uptake. <h4>Methods</h...

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Literature Corpus work: 247ebc5f-a171-5bec-9872-7632f35f6cb1
DOI: 10.1101/183319

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