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Article

Atrial-Specific Gene Delivery Using an Adeno-Associated Viral Vector

17 Jan 2019

Abstract excerpt

Rationale: Somatic overexpression in mice using an adeno-associated virus (AAV) as gene transfer vectors has become a valuable tool to analyze the roles of specific genes in cardiac diseases. The lack of atrial-specific AAV vector has been a major obstacle for studies into the pathogenesis of atrial diseases. Moreover, gene therapy studies for atrial fibrillation would benefit from atrial-specific vectors. Atrial...

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PMID: 30582449
DOI: 10.1161/circresaha.118.313811

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