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Article

An Emerging Adeno-Associated Viral Vector Pipeline for Cardiac Gene Therapy

28 Oct 2013

Abstract excerpt

The naturally occurring adeno-associated virus (AAV) isolates display diverse tissue tropisms in different hosts. Robust cardiac transduction in particular has been reported for certain AAV strains. Successful applications of these AAV strains in preclinical and clinical settings with a focus on treating cardiovascular disease continue to be reported. At the same time, these studies have highlighted challenges...

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PMID: 24164238
DOI: 10.1089/hum.2013.2515

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