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Article

Cardiac gene therapy with adeno-associated virus-based vectors

16 Feb 2017

Abstract excerpt

PURPOSE OF REVIEW: Cardiac gene therapy with adeno-associated virus (AAV)-based vectors is emerging as an entirely new platform to treat, or even cure, so far intractable cardiac disorders. This review describes our current knowledge of cardiac AAV gene therapy with a particular focus on the biggest obstacle for the successful translation of cardiac AAV gene therapy into the clinic, namely the efficient delivery...

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PMID: 28169951
DOI: 10.1097/hco.0000000000000386

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