Article

Strategy for selective acquisition of transgenic marmosets using the piggyBac transposon system

2022-08-02

Abstract excerpt

Transgenic (Tg) nonhuman primates (NHPs) are excellent potential models due to their physiological similarities with humans. In NHPs, the lentiviral vector is the only available transgenesis method, but transgene sizes are limited. The piggyBac (PB) transposon system is a DNA element sandwiched between two terminal inverted repeats (TRs) that allows transposases to introduce larger genes than lentiviral vectors. H...

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Literature Corpus work: 24662e91-4ae4-51d0-b743-35621a131975
DOI: 10.1101/2022.08.02.502441

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