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Production of α1,3‐galactosyltransferase gene knockout pigs expressing both human decay‐accelerating factor and <i>N</i>‐acetylglucosaminyltransferase III

1 Apr 2005

Abstract excerpt

Heterozygous alpha 1,3-galactosyltransferase (GT) gene knockout pigs were produced with transgenic pig fetal cells expressing both human decay-accelerating factor (hDAF) and N-acetylglucosaminyltransferase III (GnT-III). In this study, we assessed the gene targeting efficiency in the transgenic pig fetal cells derived from different fetal tissues such as brain, skin, heart, and liver, or fetal carcass. Targeted...

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PMID: 15806557
DOI: 10.1002/mrd.20305

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