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Article

Validation of a Large Custom-Designed Pharmacogenomics Panel on an Array Genotyping Platform.

The journal of applied laboratory medicine - 1 Nov 2021

Tang Nga Yeung, Pei Xun, George David, House Larry, Danahey Keith, Lipschultz Elizabeth, Ratain Mark J, O'Donnell Peter H, Yeo Kiang-Teck J, van Wijk Xander M R

Abstract excerpt

BACKGROUND: Pharmacogenomics has the potential to improve patient outcomes through predicting drug response. We designed and evaluated the analytical performance of a custom OpenArray® pharmacogenomics panel targeting 478 single-nucleotide variants (SNVs). METHODS: Forty Coriell Institute cell line (CCL) DNA samples and DNA isolated from 28 whole-blood samples were used for accuracy evaluation. Genotyping calls...

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Source

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Identifiers

PMID: 34263311
DOI: 10.1093/jalm/jfab056
PMCID: PMC8561785

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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