Article

ECNano: A Cost-Effective Workflow for Target Enrichment Sequencing and Accurate Variant Calling on 4,800 Clinically Significant Genes Using a Single MinION Flowcell

2021-04-06

Abstract excerpt

<h4>Background</h4> The application of long-read sequencing using the Oxford Nanopore Technologies (ONT) MinION sequencer is getting more diverse in the medical field. Having a high sequencing error of ONT and limited throughput from a single MinION flowcell, however, limits its applicability for accurate variant detection. Medical exome sequencing (MES) targets clinically significant exon regions, allowing rapid...

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Literature Corpus work: a545cf22-6170-5c12-8b62-c76c0e893210
DOI: 10.1101/2021.04.05.438455

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