Article

Ifit1 regulates norovirus infection and enhances the interferon response in murine macrophage-like cells

2019-04-17

Abstract excerpt

<h4>Background</h4> Norovirus, also known as the winter vomiting bug, is the predominant cause of non-bacterial gastroenteritis worldwide. Disease control is predicated on a robust innate immune response during the early stages of infection. Double-stranded RNA intermediates generated during viral genome replication are recognised by host innate immune sensors in the cytoplasm, activating the strongly antiviral i...

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Literature Corpus work: 24262ced-268b-534a-b046-365c0dd0a9c8
DOI: 10.1101/611236

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