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Article

Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation

12 Aug 2019

Abstract excerpt

Knowledge of the host factors required for norovirus replication has been hindered by the challenges associated with culturing human noroviruses. We have combined proteomic analysis of the viral translation and replication complexes with a CRISPR screen, to identify host factors required for norovirus infection. The core stress granule component G3BP1 was identified as a host factor essential for efficient human...

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PMID: 31403400
DOI: 10.7554/elife.46681

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Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translationPMID 31403400Read ↗

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