Article

The dietary emulsifier polysorbate-80 induces lipid accumulation and cell death in intestinal epithelial cells via ferroptosis

2025-08-31

Abstract excerpt

<h4>Summary</h4> Chronic inflammatory and metabolic diseases are major global health issues increasingly linked to dietary factors. Consumption of dietary emulsifiers like polysorbate-80 (p80), common in ultra-processed foods and pharmaceuticals, has raised concerns about gut health. RNA sequencing on intestinal epithelial cells (IECs) exposed to p80 revealed increased expression of ferroptosis-associated genes a...

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Literature Corpus work: 2416a44e-8ed3-589a-9e04-d1777d35a2a2
DOI: 10.1101/2025.08.29.673091

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